GPCRdb

CHEMBL423694

Agent/drug
Bioactivity

CHEMBL423694

SMILES	CCN(CC)C(=O)c1ccc(C(=C2CCNCC2)c2cccc(OC)c2)cc1
InChIKey	UWERJSHTOGBZDV-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	378.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Rat	Opioid	A	pKi	8.30	8.30	8.30	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pKi	5.00	5.00	5.00	ChEMBL
μ	OPRM	Rat	Opioid	A	pKi	5.00	5.00	5.00	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Mouse	Opioid	A	pIC50	6.90	6.90	6.90	ChEMBL
δ	OPRD	Human	Opioid	A	pIC50	8.81	8.81	8.81	ChEMBL
δ	OPRD	Human	Opioid	A	pEC50	7.86	7.86	7.86	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	5.28	5.28	5.28	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL423694

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.