CHEMBL4099851


SMILES C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(F)c1)c1ccc(C(=O)O)cc1
InChIKey FKXDPPYCCKCVCW-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 414.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 Q9TU16 Dog Prostanoid A pKi 7.42 7.42 7.42 ChEMBL
EP4 PE2R4 Rat Prostanoid A pKi 8.21 8.21 8.21 ChEMBL
EP4 PE2R4 Rat Prostanoid A pKd 8.34 8.34 8.34 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKd 9.0 9.0 9.0 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 5.74 5.74 5.74 ChEMBL
EP4 PE2R4 Human Prostanoid A pKd 8.97 8.97 8.97 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 9.01 9.01 9.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pIC50 5.72 5.72 5.72 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 7.79 8.21 8.62 ChEMBL