CHEMBL4289783


SMILES Fc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(-c2ccccc2)c1
InChIKey GPVZPQVIHIFYGO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 431.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 7.55 7.55 7.55 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.48 8.48 8.48 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.55 7.73 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database