GPCRdb

CHEMBL427844

Agent/drug
Bioactivity

CHEMBL427844

SMILES	CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1
InChIKey	YWMJHCFRFHOSCO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	7
Molecular weight (Da)	554.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Human	Prostanoid	A	pKi	10.00	10.00	10.00	ChEMBL
EP₃	PE2R3	Human	Prostanoid	A	pKi	6.30	6.30	6.30	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Human	Prostanoid	A	pIC50	9.40	9.40	9.40	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pIC50	6.80	6.80	6.80	ChEMBL
TP	TA2R	Human	Prostanoid	A	pIC50	8.60	8.60	8.60	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL427844

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.