GPCRdb

CHEMBL427862

Agent/drug
Bioactivity

CHEMBL427862

SMILES	CCNC(=O)Oc1ccc2c(c1)C13CCCCC1C(C2)N(CC1CC1)CC3
InChIKey	RVWFZRGYOXCUSN-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	4
Molecular weight (Da)	368.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	8.55	8.55	8.55	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	9.85	9.85	9.85	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	9.54	9.54	9.54	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Human	Opioid	A	pEC50	8.92	8.92	8.92	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	8.00	8.00	8.00	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	8.62	8.62	8.62	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL427862

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.