CHEMBL4299892


SMILES Cc1cc(C)c(OCCOCCN2CCN(CCc3ccccc3)CC2)c(C)c1
InChIKey YQADZRAXENHBMD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 396.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 6.11 6.11 6.11 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.67 5.67 5.67 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.55 5.55 5.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.93 5.93 5.93 ChEMBL