CHEMBL4300609


SMILES Cc1cccc(OCCOCCN2CCN(CCc3ccccc3)CC2)c1C
InChIKey UZBAJYSQVMDJAM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 382.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 7.44 7.44 7.44 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.66 6.66 6.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.16 5.16 5.16 ChEMBL