CHEMBL4300710


SMILES COc1ccc(N2CCN(CCCOc3c(C)cc(C)cc3C)CC2)cc1
InChIKey MGOVFKYGYIQOQX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 5.67 5.67 5.67 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.52 5.52 5.52 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.84 6.84 6.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.22 6.22 6.22 ChEMBL