GPCRdb

CHEMBL1243367

Agent/drug
Bioactivity

CHEMBL1243367

SMILES	FC(F)(F)c1ccc(SCC(c2ccncc2)c2c[nH]cn2)cc1
InChIKey	YXEZVHWJNRFKSI-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	5
Molecular weight (Da)	349.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₁	HRH1	Human	Histamine	A	pKi	6.27	6.27	6.27	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	6.70	6.70	6.70	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	7.77	7.77	7.77	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pEC50	6.85	6.85	6.85	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL1243367

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.