CHEMBL442242


SMILES Cc1nn(C)cc1-c1ccc2cc(CCN3CCC[C@H]3C)ccc2n1
InChIKey GGGPOYPNHTZKFQ-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.51 8.72 8.8 ChEMBL
H3 HRH3 Human Histamine A pKi 9.3 9.34 9.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pEC50 8.24 8.24 8.24 ChEMBL
H3 HRH3 Human Histamine A pEC50 8.7 8.7 8.7 ChEMBL
H3 HRH3 Human Histamine A pIC50 7.37 7.37 7.37 ChEMBL