CHEMBL4163428


SMILES CN1CCN(c2ccc3c(c2)CN(C(=O)OCc2ccccc2)C3)CC1
InChIKey UETLZTFBKJSNHG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.84 5.84 5.84 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.34 6.34 6.34 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.59 6.59 6.59 ChEMBL
H2 HRH2 Human Histamine A pKi 6.54 6.54 6.54 ChEMBL
H1 HRH1 Human Histamine A pKi 6.32 6.32 6.32 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.31 6.31 6.31 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
H3 HRH3 Human Histamine A pKi 6.32 6.32 6.32 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.52 6.52 6.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.99 5.99 5.99 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.58 5.58 5.58 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.74 5.74 5.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database