CHEMBL4165863


SMILES O=C(OCc1ccccc1)N1CCc2ccc(N3CCN(C4CCCC4)CC3)cc2C1
InChIKey UQSVESYMRYILGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 419.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.76 5.76 5.76 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.13 5.13 5.13 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.75 5.75 5.75 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 5.64 5.64 5.64 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.61 5.61 5.61 ChEMBL
H2 HRH2 Human Histamine A pKi 5.75 5.75 5.75 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.57 5.57 5.57 ChEMBL
H1 HRH1 Human Histamine A pKi 6.47 6.47 6.47 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 5.46 5.46 5.46 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.3 6.3 6.3 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
H3 HRH3 Human Histamine A pKi 6.52 6.52 6.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.93 5.93 5.93 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.02 6.02 6.02 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database