GPCRdb

fulvestrant

Agent/drug
Bioactivity

fulvestrant

SMILES	C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)[C@H]3[C@@H]1CC[C@@H]2O
InChIKey	VWUXBMIQPBEWFH-WCCTWKNTSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	14
Molecular weight (Da)	606.3

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central GPCRdb
Structure pdb	8XOI

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

GPER	GPER1	Human	Estrogen (G protein-coupled)	A	pKi	7.00	7.00	7.00	Guide to Pharmacology

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

GPER	GPER1	Human	Estrogen (G protein-coupled)	A	pEC50	8.15	8.15	8.15	Drug Central

Showing 1 to 1 of 1 entry

fulvestrant

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central GPCRdb
Structure pdb	8XOI

Compound is not listed as a drug.