CHEMBL418499


SMILES Cn1c(=O)sc2cc(CCN3CCN(c4cccc(C(F)(F)F)c4)CC3)ccc21
InChIKey YURVPEXVKWCAQY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 421.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pIC50 6.22 6.22 6.22 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pIC50 6.4 6.4 6.4 ChEMBL
D2 DRD2 Bovine Dopamine A pIC50 6.7 6.7 6.7 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 7.16 7.16 7.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 9.0 9.0 9.0 ChEMBL