GPCRdb

CHEMBL4469777

Agent/drug
Bioactivity

CHEMBL4469777

SMILES	CCc1cccc(N2CCN(C)CC2)c1Cl
InChIKey	WDYXVLOKALEPOS-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	0
Rotatable bonds	2
Molecular weight (Da)	238.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.39	7.39	7.39	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	8.49	8.49	8.49	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	8.40	8.40	8.40	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.24	7.24	7.24	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.87	7.87	7.87	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	7.05	7.05	7.05	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	7.56	7.56	7.56	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	6.15	6.15	6.15	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL4469777

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.