GPCRdb

CHEMBL4471669

Agent/drug
Bioactivity

CHEMBL4471669

SMILES	CCCCN1CCN(c2cccc(CC)c2Cl)CC1
InChIKey	YTGXGXKZORFSRT-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	280.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.43	7.43	7.43	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	7.28	7.28	7.28	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.65	6.65	6.65	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	8.53	8.53	8.53	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	9.44	9.44	9.44	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	7.19	7.19	7.19	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	7.32	7.32	7.32	ChEMBL
D₃	DRD3	Human	Dopamine	A	pIC50	7.20	7.20	7.20	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	6.23	6.23	6.23	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL4471669

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.