CHEMBL4241081


SMILES O=S(=O)(c1cccc2ncccc12)N1CCCC[C@@H]1CCN1CCN(c2nsc3ccccc23)CC1
InChIKey GGVSMYIRKIXVCG-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 521.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.02 6.02 6.02 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database