CHEMBL4537998


SMILES O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)N1CCc2ncccc2[C@@H]1c1ccc(Cl)cc1
InChIKey FMQWOAKTQPLQBR-SANMLTNESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 473.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
LH LSHR Rat Glycoprotein hormone A pIC50 7.64 7.64 7.64 ChEMBL
LH LSHR Human Glycoprotein hormone A pIC50 5.6 6.11 7.02 ChEMBL
TSH TSHR Human Glycoprotein hormone A pIC50 5.64 5.64 5.64 ChEMBL