CHEMBL4539444


SMILES N=C(N)N(CCCCN1CCN(CCCCCCCOc2ccccc2)CC1)Cc1ccccc1
InChIKey FETNGKPEELWQKP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 16
Molecular weight (Da) 479.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Guinea pig Histamine A pKd 8.21 8.21 8.21 ChEMBL
H1 HRH1 Guinea pig Histamine A pKd 6.7 6.7 6.7 ChEMBL
H3 HRH3 Rat Histamine A pKi 7.9 7.9 7.9 ChEMBL
H4 HRH4 Human Histamine A pKi 5.49 5.49 5.49 ChEMBL
H3 HRH3 Human Histamine A pKi 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database