CHEMBL1258036


SMILES O=C(CCCN1CCN(c2cc3ccc2CCc2ccc(cc2)CC3)CC1)c1ccc(F)cc1
InChIKey FMZYTGKVWBHUEI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 456.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.0 8.0 8.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.66 7.69 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database