CHEMBL430122


SMILES COc1ccc(NC(=O)N2CCC(c3c[nH]c4ccc(C#N)cc34)CC2)cc1N1CCN(C)CC1
InChIKey GJIIWFJJJBJFMX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 472.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Rat 5-Hydroxytryptamine A pIC50 6.4 6.4 6.4 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 6.57 6.57 6.57 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.63 6.63 6.63 ChEMBL