CHEMBL4302457


SMILES Cc1cc(OCCCN2CCN(c3ccccc3)CC2)ccc1Cl
InChIKey NCKUXAJTZOKPEP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 344.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.05 7.05 7.05 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.03 7.03 7.03 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.12 7.12 7.12 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.52 6.52 6.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.24 5.24 5.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 4.07 4.07 4.07 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.54 6.54 6.54 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.12 6.12 6.12 ChEMBL