CHEMBL4586057


SMILES C[C@H]1C(=O)N(c2ccc(Cl)cc2)C(=O)N1Cc1ccccc1
InChIKey GHAJNZREWTZYQJ-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 314.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Human Frizzled F pKi 7.48 7.48 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Mouse Frizzled F pIC50 7.23 7.23 7.23 ChEMBL