CHEMBL435949


SMILES COc1ccccc1N1CCN(Cc2c[nH]c3ncccc23)CC1
InChIKey IDBBDQXTEVOOKW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.85 8.85 8.85 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.99 6.99 6.99 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.36 6.36 6.36 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.13 5.13 5.13 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.64 5.64 5.64 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database