CHEMBL437314


SMILES C[C@@H](N)Cn1ncc2ccc(O)cc21
InChIKey WBYHTZYHAFNBKW-SSDOTTSWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 191.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pEC50 7.07 7.07 7.07 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pEC50 7.06 7.06 7.06 ChEMBL
α2B ADA2B Human Adrenoceptors A pEC50 5.33 5.33 5.33 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 5.25 5.25 5.25 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 5.7 5.7 5.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 5.54 5.54 5.54 ChEMBL