CHEMBL439560


SMILES CC(C)C[C@H](N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)N2CCCC2=O)CC1
InChIKey GWQJQMUYAJRYAV-AZGAKELHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 564.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Rat Melanocortin A pKi 8.04 8.04 8.04 ChEMBL
MC4 MC4R Mouse Melanocortin A pKi 8.26 8.26 8.26 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.0 6.0 6.0 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.75 5.75 5.75 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.96 7.96 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pEC50 5.39 5.39 5.39 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 6.29 6.29 6.29 ChEMBL