CHEMBL439934


SMILES COCc1cccc(C[C@H](O)/C=C/[C@H]2[C@H](O)C[C@@H](F)[C@@H]2C/C=C/CCCC(=O)O)c1
InChIKey IGRHMJRVBYYCFZ-NGTZFMKBSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 12
Molecular weight (Da) 420.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Mouse Prostanoid A pKi 5.77 5.77 5.77 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 7.24 7.24 7.24 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 8.47 8.47 8.47 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 7.03 7.03 7.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Mouse Prostanoid A pEC50 7.85 7.85 7.85 ChEMBL