CHEMBL4596606


SMILES CN1CCCN(c2ccnc(NCC(C)(C)C)n2)CC1
InChIKey OVINBYPHDFDIOA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 277.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.2 7.2 7.2 ChEMBL
H3 HRH3 Human Histamine A pKi 5.62 5.62 5.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 6.08 6.77 7.45 ChEMBL
H4 HRH4 Rat Histamine A pEC50 6.48 7.71 8.93 ChEMBL
H4 HRH4 Human Histamine A pEC50 6.86 7.29 7.71 ChEMBL