CHEMBL441618


SMILES CN1CCc2ccccc2Cc2[nH]c3ccccc3c2CC1
InChIKey YEWGIGCYIAMFMA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 290.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.9 8.05 8.12 ChEMBL
D1 DRD1 Rat Dopamine A pKi 10.1 10.1 10.1 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.22 8.22 8.22 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.97 6.97 6.97 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.22 8.35 8.73 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.39 7.52 7.59 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.35 7.46 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.75 4.78 4.8 ChEMBL