CHEMBL460349


SMILES CC[C@H]1C(=O)N([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)[C@H](N)Cc1ccc(F)cc1
InChIKey YBCXRFXRMKTZQS-ZNZIZOMTSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 504.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.0 5.0 5.0 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.02 6.02 6.02 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 5.77 5.77 5.77 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.62 6.62 6.62 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.51 7.51 7.51 ChEMBL