GPCRdb

CHEMBL460138

Agent/drug
Bioactivity

CHEMBL460138

SMILES	CCC[C@H]1C(=O)N([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)[C@H](N)Cc1ccc(F)cc1
InChIKey	FBIBREHNRFMLIZ-PVHODMMVSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	9
Molecular weight (Da)	518.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Human	Melanocortin	A	pKi	5.00	5.00	5.00	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pKi	6.14	6.14	6.14	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	7.12	7.12	7.12	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Human	Melanocortin	A	pEC50	5.82	5.82	5.82	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pEC50	6.83	6.83	6.83	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pEC50	7.55	7.55	7.55	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL460138

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.