CHEMBL466634


SMILES Fc1ccc(-c2ncco2)c(C2Cc3nccn3C2)c1
InChIKey NOCWBSIDJYRURZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 269.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 6.33 6.33 6.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pEC50 8.52 8.52 8.52 ChEMBL
α1D ADA1D Human Adrenoceptors A pEC50 6.56 6.56 6.56 ChEMBL
α1B ADA1B Human Adrenoceptors A pEC50 6.0 6.0 6.0 ChEMBL