CHEMBL117537


SMILES O=C(CCCc1ccccc1)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
InChIKey VGBOISIRCIDEGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 476.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pIC50 5.73 5.73 5.73 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.67 5.67 5.67 ChEMBL
H1 HRH1 Human Histamine A pIC50 5.71 5.71 5.71 ChEMBL
D4 DRD4 Human Dopamine A pIC50 6.55 6.55 6.55 ChEMBL
D1 DRD1 Human Dopamine A pIC50 5.56 5.56 5.56 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 5.11 5.11 5.11 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.39 5.39 5.39 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.12 6.12 6.12 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.02 6.02 6.02 ChEMBL
δ OPRD Human Opioid A pIC50 5.43 5.43 5.43 ChEMBL
κ OPRK Human Opioid A pIC50 5.67 5.67 5.67 ChEMBL
μ OPRM Human Opioid A pIC50 5.42 5.42 5.42 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pIC50 5.26 5.26 5.26 ChEMBL
H2 HRH2 Human Histamine A pIC50 5.7 5.7 5.7 ChEMBL