CHEMBL467588


SMILES CC(C)[C@H](NC(=O)CCN(C)C)c1cc(Cl)ccc1N1CCN(C(=O)[C@H](C)Cc2ccc(Cl)cc2)CC1
InChIKey FISNMOAZOFAUNZ-PIKZIKFNSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 546.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.21 5.21 5.21 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.41 6.41 6.41 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.35 6.35 6.35 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.48 8.48 8.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 6.82 6.82 6.82 ChEMBL