GPCRdb

genistein

Agent/drug
Bioactivity

genistein

SMILES	O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12
InChIKey	TZBJGXHYKVUXJN-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	3
Rotatable bonds	1
Molecular weight (Da)	270.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.52	5.52	5.52	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	5.11	5.11	5.11	ChEMBL
A₁	AA1R	Rat	Adenosine	A	pKi	5.30	5.30	5.30	ChEMBL
A₁	AA1R	Human	Adenosine	A	pKi	4.93	4.93	4.93	ChEMBL
A_2A	AA2AR	Rat	Adenosine	A	pKi	4.44	4.44	4.44	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pKi	5.01	5.01	5.01	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pIC50	4.98	4.98	4.98	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pIC50	4.83	4.83	4.83	ChEMBL
A₁	AA1R	Human	Adenosine	A	pIC50	4.70	4.70	4.70	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pIC50	4.76	4.76	4.76	ChEMBL
TAS2R14	T2R14	Human	Taste 2	T2	pEC50	4.19	4.19	4.19	Guide to Pharmacology
TAS2R39	T2R39	Human	Taste 2	T2	pEC50	4.31	4.31	4.31	Guide to Pharmacology
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	6.00	6.00	6.00	ChEMBL

Showing 1 to 7 of 7 entries

genistein

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Compound is not listed as a drug.