CHEMBL4469309


SMILES COc1ccc2c(c1)c(C1=CCNCC1)cn2S(=O)(=O)c1cncc2ccccc12
InChIKey GSHJIIAYCVNFDZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 419.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.11 5.11 5.11 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.47 5.47 5.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.48 5.48 5.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database