CHEMBL473662


SMILES CN1CCN(c2cc(N)nc(N)n2)CC1
InChIKey RBHNSRTVBDSNLG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 208.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.28 6.41 6.54 ChEMBL
H3 HRH3 Human Histamine A pKi 5.97 5.97 5.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Rat Histamine A pEC50 6.66 6.66 6.66 ChEMBL