GPCRdb

CHEMBL467771

Agent/drug
Bioactivity

CHEMBL467771

SMILES	CNCC(=O)N[C@H](c1cccc(F)c1N1CCN(C(=O)[C@H](C)Cc2ccc(Cl)cc2)CC1)C(C)C
InChIKey	DJUMIBAWSMGVLY-CLOONOSVSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	9
Molecular weight (Da)	502.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₃	MC3R	Human	Melanocortin	A	pKi	6.24	6.24	6.24	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	8.00	8.00	8.00	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pKi	5.96	5.96	5.96	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₄	MC4R	Human	Melanocortin	A	pIC50	6.47	6.47	6.47	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL467771

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.