GPCRdb

CHEMBL469189

Agent/drug
Bioactivity

CHEMBL469189

SMILES	C[C@H]1C2Cc3ccc4c(N)ncnc4c3[C@@]1(C)CCN2CC1CC1
InChIKey	ZYYCSXTURJNMLS-DPZUSKQMSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	322.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	6.92	6.92	6.92	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	9.00	9.00	9.00	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	9.26	9.26	9.26	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Human	Opioid	A	pIC50	5.89	5.89	5.89	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	7.55	7.55	7.55	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL469189

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.