CHEMBL4483554


SMILES COc1ccc2[nH]cc(C3CC(=O)N(CCCCN4CCC(c5c[nH]c6ccccc56)CC4)C3=O)c2c1
InChIKey ZUDVHWCNTPJCDE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 498.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.09 7.09 7.09 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.2 8.2 8.2 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database