GPCRdb

CHEMBL473699

Agent/drug
Bioactivity

CHEMBL473699

SMILES	Cc1nc2cc3c(cc2[nH]1)[C@@]1(C)CCN(CC2CC2)C(C3)[C@@H]1C
InChIKey	PVOGJENIZFDIAO-BFKPJKFSSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	309.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	7.75	7.75	7.75	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	10.30	10.30	10.30	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	9.11	9.11	9.11	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Human	Opioid	A	pEC50	8.24	8.24	8.24	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	4.96	4.96	4.96	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	7.75	7.75	7.75	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL473699

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.