CHEMBL4519266


SMILES COc1ccc(-c2ccc(CNCCc3c[nH]c4ccc(OC)cc34)o2)cc1
InChIKey VOQWGUWQIPPYSL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 376.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.48 5.48 5.48 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.05 7.05 7.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.87 5.87 5.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database