GPCRdb

2-METHYLHISTAMINE

Agent/drug
Bioactivity

2-METHYLHISTAMINE

SMILES	Cc1ncc(CCN)[nH]1
InChIKey	XDKYTXBAVJELDQ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	2
Molecular weight (Da)	125.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	H₁

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₄	HRH4	Human	Histamine	A	pKi	6.10	6.10	6.10	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₁	HRH1	Human	Histamine	A	pEC50	6.10	6.10	6.10	ChEMBL
H₄	HRH4	Human	Histamine	A	pEC50	5.40	5.40	5.40	ChEMBL

Showing 1 to 2 of 2 entries

2-METHYLHISTAMINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	H₁

Compound is not listed as a drug.