CHEMBL4524981


SMILES CN1CCN(c2nc(N)nc(COc3cccc(Cl)c3)n2)CC1
InChIKey PGDKRINPWAQWOE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 334.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.24 5.24 5.24 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.12 5.12 5.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.17 6.17 6.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database