GPCRdb

CHEMBL474755

Agent/drug
Bioactivity

CHEMBL474755

SMILES	COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(OC(=O)/C=C/c5ccccc5)[C@@H](C2)N(CC2CC2)CC[C@]314
InChIKey	WGDLNMCFJZEUHA-ATTGEPADSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	0
Rotatable bonds	6
Molecular weight (Da)	485.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	6.75	6.75	6.75	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	8.37	8.37	8.37	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	8.60	8.60	8.60	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	6.37	6.37	6.37	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	7.58	7.58	7.58	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	7.46	7.46	7.46	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL474755

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.