CHEMBL4782762


SMILES CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O
InChIKey MKWJFYTWCUVRPG-SSNHPIBPSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 6
Rotatable bonds 15
Molecular weight (Da) 706.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Mouse Melanocortin A pKd 5.0 5.0 5.0 ChEMBL
MC4 MC4R Mouse Melanocortin A pKi 5.0 5.0 5.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 7.51 7.51 7.51 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 6.8 6.8 6.8 ChEMBL
MC3 MC3R Mouse Melanocortin A pEC50 6.82 6.82 6.82 ChEMBL