CHEMBL4572158


SMILES O=S(=O)(c1ccc2cccnc2c1)n1cc(C2=CCNCC2)c2cc(Cl)ccc21
InChIKey MSWZLRLBKLDMKM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 423.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.13 5.13 5.13 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.59 5.59 5.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.61 5.61 5.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.93 5.93 5.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database