CHEMBL4597576


SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey KOKXORZIPKJNJL-ZYBCLOSLSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 6
Rotatable bonds 18
Molecular weight (Da) 909.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.41 7.41 7.41 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.97 8.97 8.97 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.87 7.87 7.87 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.83 9.83 9.83 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.06 9.06 9.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database