CHEMBL4845733


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=S)NC[C@@H](C)c1ccccc1
InChIKey VCBVQPPOGCHJKE-GFCCVEGCSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 390.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 6.37 6.37 6.37 ChEMBL
H1 HRH1 Human Histamine A pKi 4.28 4.28 4.28 ChEMBL
H3 HRH3 Human Histamine A pKi 4.08 4.08 4.08 ChEMBL
H4 HRH4 Human Histamine A pKi 4.49 4.49 4.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database