GPCRdb

CHEMBL481366

Agent/drug
Bioactivity

CHEMBL481366

SMILES	CC1(N2CCC(n3c([C@H]4CCCNC4)nc4ccccc43)CC2)CCCCCCC1
InChIKey	CYYNMPPFEJPBJD-NRFANRHFSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	408.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	6.78	6.78	6.78	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	8.04	8.04	8.04	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	9.23	9.23	9.23	ChEMBL
NOP	OPRX	Human	Opioid	A	pKi	10.00	10.00	10.00	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	6.29	6.29	6.29	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	8.08	8.08	8.08	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	7.64	7.64	7.64	ChEMBL
NOP	OPRX	Human	Opioid	A	pEC50	5.61	7.83	10.60	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL481366

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.